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Mission Statement

Our research laboratory focuses on innovating neuromodulation technologies to improve quality of life for people with neurological disorders. Deep brain stimulation (DBS) is one such technology, which has helped numerous people living with Parkinson's disease, dystonia, and essential tremor reclaim control over their motor function. DBS therapy involves placing tiny electrodes in regions of the brain that exhibit pathological activity and then stimulating those regions with continuous pulses of energy. We focus on understanding how the brain responds and adapts to stimulation-based therapies from a combination of computational and experimental perspectives. These studies in turn provide us with a rationale to develop, evaluate, and translate new approaches for improving patient care.

Recent News News archives

August 1, 2015
Joe Xiao published his paper, "Spherical statistics of neuronal populations modulated by deep brain stimulation," in the Journal of Neuroscience Methods. Well done, Joe!

July 13, 2015
Joe Xiao and Edgar Peña published their paper, "Theoretical optimization strategies for directionally segmented deep brain stimulation electrode arrays," in IEEE Transactions on Biomedical Engineering. Well done, Joe and Edgar!

July 2, 2015
Laura Zitella published her paper, "Subject-specific computational modeling of DBS in the PPTg area" in Frontiers of Computational Neuroscience. Well done, Laura!

June 16, 2015
Filippo Agnesi published his paper, "Fidelity of frequency and phase entrainment of circuit-level spike activity during DBS," in the Journal of Neurophysiology. Well done, Filippo!

Contact Information

Dr. Matthew D. Johnson

6-134 Hasselmo Hall, 312 Church St SE, Minneapolis, MN, 55455

P: 612-626-6492 | F: 612-626-6583

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